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Multimodal Analgesia For Postoperative Pain Control. Lidocaine may be delivered through a transdermal patch although the analgesic efficacy for postoperative pain is uncertain. Although slight variations exist we will define multimodal analgesia as the use of several classes of analgesics with varying mechanisms of action used together to improve pain control decrease overreliance on opioids for analgesia. 29 Lidocaine patches are generally well tolerated and compared with other opioid and nonopioid analgesics have a very favorable low-risk adverse effect profile. Multimodal analgesia is currently recommended for effective postoperative pain.
Multimodal analgesia is a term that refers to the use of several different analgesic medications or techniques simultaneously to target multiple receptors within nociceptive and neuropathic pathways thus reducing acute postoperative pain and the surgical stress response as well as potentially impacting the mechanistic chain of events that. Multimodal analgesia which combines analgesic drugs from different classes and employs analgesic techniques that target different mechanisms of pain is recommended in the treatment of acute postoperative and trauma-related pain because its synergistic effect maximizes pain relief at lower analgesic doses thereby reducing the risk of adverse drug effects. Nevertheless opioids still have a critical role in acute postoperative pain management especially for procedures where a primary regional neuraxial or local infiltration is not possible. Many studies have reported that both preemptive and multimodal analgesia improve postoperative pain control. Lidocaine may be delivered through a transdermal patch although the analgesic efficacy for postoperative pain is uncertain. Single analgesics either opioid or nonsteroidal.
Nevertheless opioids still have a critical role in acute postoperative pain management especially for procedures where a primary regional neuraxial or local infiltration is not possible.
Multimodal Analgesia for Postoperative Pain Management 181 A lower incidence of adverse effects and impr oved analgesia has been demonstrated with multimodal analgesia techniques which may provide for shorter hospitalization times improved recovery and function and possibly decreased heal thcare costs Buvanendran Kroin 2009. Multimodal analgesia is needed for acute postoperative pain management due to adverse effects of opioid analgesics which can impede recovery. Lidocaine may be delivered through a transdermal patch although the analgesic efficacy for postoperative pain is uncertain. Ketoprofen at doses of 25 mg to 100 mg is an effective analgesic in moderate to severe acute postoperative pain with an NNT for at least 50 pain relief of 33 with a 50 mg dose. The opioid-sparing multimodal analgesic options discussed above are integral for optimal pain management in the perioperative period. Different analgesics act on different receptors enzymes and ionic channels creating an additive or synergistic response.