14
Apr
Can Mthfr Affect Cholesterol. Therefore MTHFR gene polymorphism may affect DNA methylation level and further influence atherosclerosis morbidity. More research is needed to determine the true impact if any associated with the variants. Your MTHFR status may or may not be affecting your health. The following is a list of cardiovascular conditions where MTHFR combined with an elevated homocysteine could be playing a role.
Doing so may bring to light dietary deficiencies thyroid disease diabetes high cholesterol or life-style factors physical inactivity smoking and obesity which can impact homocystine levels. While the presence of hyperhomocysteinemia in people with hypothyroidism may suggest an association with the MTHFR mutationa link popularly shared on many thyroid disease blogsit is important to note that hypothyroidism can trigger high homocysteine levels irrespective of whether the MTHFR mutation is there or not. Homocysteine is an amino acid that works to maintain the bodys cells. Theres no scientific evidence that MTHFR gene mutations cause recurrent pregnancy loss but women whove had multiple pregnancy. The truth is the crusade against cholesterol is misguided medicine which has caused more harm than good. Hcy level is closely related to DNA methylation level 1719 and it can affect atherosclerosis occurrence and development by regulating DNA methylation level.
This relationship may be in part due to altered epigenetic regulation of Methylenetetrahydrofolate Reductase MTHFR.
The MTHFR gene mutation was once thought to effect 3 5 of the population. Therefore MTHFR gene polymorphism may affect DNA methylation level and further influence atherosclerosis morbidity. The only way the body has to remove the offending substances that are contained in these unsuspecting foods is methylation which means consuming these foods is much more costly to the bodys resources requiring larger amounts of vitamin B12 metabolized folate MTHF methionine betaine glycine. Doing so may bring to light dietary deficiencies thyroid disease diabetes high cholesterol or life-style factors physical inactivity smoking and obesity which can impact homocystine levels. MTHFR mutation may be adding fuel to the fire of cardiovascular problems. But you already know that.